Aug 29 2021
The 2012 paper in Science about the CRISPR/Cas9 system has been hailed as the greatest breakthrough in biology since Crick and Watson’s discovery of the DNA double helix in 1953. It has earned its two Principal Investigators (PI), Emmanuelle Charpentier and Jennifer Doudna, the 2020 Nobel prize in chemistry. Laypersons cannot really follow this paper but what we can better understand is how the research team worked. And it is remarkable.