Apr 2 2021
COVID-19 Pfizer Vaccine Study On Teens
Pfizer-BioNTech just announced the results of a COVID-19 vaccine clinical trial of 12- to 15-year olds. Because the vaccinated group had 0 infections, the news media jumped to the conclusion that the vaccine has “100% efficacy” on 12- to 15-year olds. That is what the chyron said on NBC news. A look at the published trial results and quick analysis with current methods confirms that the vaccine works for that population but not that it eliminates 100% of the infections.
Apr 16 2021
Measuring QC Efficacy: A Proposal
[The featured image is of a Vietnamese satellite undergoing final test in Japan]
As Jay Bitsack pointed out in his comments on LinkedIn about my previous post, the portability of a method from epidemiology to manufacturing quality is not a foregone conclusion. Formally, the logic of validating a vaccine seems applicable to the solution of a quality problem. They look similar when you consider only outcomes in terms of infection rates or the proportion of defectives.
There are differences between data sets from a clinical trial and tests run before and after a process change in production that may affect the applicability of a method. We examine the conditions for the approach developed by Carlo Graziani for vaccine efficacy to cross over to quality control. Then we work out the math of Graziani’s method and the means to apply it.
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By Michel Baudin • Laws of nature 0 • Tags: Bayesian Statistics, Efficacy, Manufacturing, Quality, Quality Assurance, Quality Control